Review Article| Volume 42, ISSUE 2, P307-312, March 2012

Xylitol Toxicosis in Dogs

Published:January 09, 2012DOI:
      The 5-carbon sugar alcohol xylitol is used as a sweetener in many products including gums, candies, and baked goods. In recent years the use of xylitol has increased due to the popularity of low-carbohydrate diets and low–glycemic index foods.
      • Gare F.
      The sweet miracle of xylitol.
      Xylitol also prevents oral bacteria from producing acids that damage the surfaces of teeth, leading to its inclusion in toothpaste and other oral care products.
      • Gare F.
      The sweet miracle of xylitol.
      • Cronin J.R.
      Xylitol: a sweet for healthy teeth and more.
      While xylitol is considered safe in humans, canine ingestions have resulted in severe and life-threatening signs associated with increased insulin secretion leading to hypoglycemia. Acute death due to severe hypoglycemia if untreated is possible, and liver failure may develop 1 to 3 days after xylitol ingestion.


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