Fibrinolysis is an essential component of hemostasis. It is the natural balancing
act for coagulation or thrombosis, limiting the extent of thrombus formation and ultimately
being responsible for its dissolution. During plasmin-mediated fibrinolysis, breakdown
or degradation products of fibrin are released. One of these products is D-dimer.
This reviews answers the following questions. What is D-dimer? How is it produced?
How does D-dimer differ from fibrin(ogen) degradation products (FDPs)? How can D-dimer
be used to diagnose hemostatic disorders in veterinary medicine?
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© 2003 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
